| jianjium | Date: Friday, 2013-11-08, 21:44:01 | Message # 1 |
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| Another theory is that melatonin produced in the pineal gland is the primary cause, since there are direct connections between the retina and the pineal gland. Some studies show that melatonin levels do not appear to differ between those with and without SAD. However, mice incapable of synthesizing melatonin appear to express "depression like" behaviors and melatonin receptor ligands produce antidepressant like effect in mice. Light therapy appears to be effective in treating SAD, but the exact mechanism of the effect is still unknown.
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